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Comparison of modification sites in glycated crystallin in vitro and in vivo

Glycation of α-crystallin is responsible for age- and diabetic-related cataracts, which are the main cause of blindness worldwide. We optimized the method of identification of lysine residues prone to glycation using the combination of LC-MS, isotopic labeling, and modified synthetic peptide standar...

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Detalles Bibliográficos
Autores principales:	Kielmas, Martyna, Kijewska, Monika, Kluczyk, Alicja, Oficjalska, Jolanta, Gołębiewska, Bożena, Stefanowicz, Piotr, Szewczuk, Zbigniew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365289/ https://www.ncbi.nlm.nih.gov/pubmed/25636230 http://dx.doi.org/10.1007/s00216-015-8487-7

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