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The Story of CD4(+)CD28(−) T Cells Revisited: Solved or Still Ongoing?
CD4(+)CD28(−) T cells are a unique type of proinflammatory T cells characterised by blockade of costimulatory CD28 receptor expression at the transcriptional level, which is still reversible by IL-12. In healthy individuals older than 65 years, these cells may accumulate to up to 50% of total CD4(+)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365319/ https://www.ncbi.nlm.nih.gov/pubmed/25834833 http://dx.doi.org/10.1155/2015/348746 |