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Single cell visualization of transcription kinetics variance of highly mobile identical genes using 3D nanoimaging

Multi-cell biochemical assays and single cell fluorescence measurements revealed that the elongation rate of Polymerase II (PolII) in eukaryotes varies largely across different cell types and genes. However, there is not yet a consensus whether intrinsic factors such as the position, local mobility...

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Detalles Bibliográficos
Autores principales: Annibale, Paolo, Gratton, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365385/
https://www.ncbi.nlm.nih.gov/pubmed/25788248
http://dx.doi.org/10.1038/srep09258

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