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Single cell visualization of transcription kinetics variance of highly mobile identical genes using 3D nanoimaging
Multi-cell biochemical assays and single cell fluorescence measurements revealed that the elongation rate of Polymerase II (PolII) in eukaryotes varies largely across different cell types and genes. However, there is not yet a consensus whether intrinsic factors such as the position, local mobility...
Autores principales: | Annibale, Paolo, Gratton, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365385/ https://www.ncbi.nlm.nih.gov/pubmed/25788248 http://dx.doi.org/10.1038/srep09258 |
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