SNP genotyping using TaqMan® technology: the CYP2D6*17 assay conundrum

CYP2D6 contributes to the metabolism of many clinically used drugs and is increasingly tested to individualize drug therapy. The CYP2D6 gene is challenging to genotype due to the highly complex nature of its gene locus. TaqMan® technology is widely used in the clinical and research settings for geno...

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Detalles Bibliográficos
Autores principales: Gaedigk, Andrea, Freeman, Natalie, Hartshorne, Toinette, Riffel, Amanda K., Irwin, David, Bishop, Jeffrey R., Stein, Mark A., Newcorn, Jeffrey H., Jaime, Lazara Karelia Montané, Cherner, Mariana, Leeder, J. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365394/
https://www.ncbi.nlm.nih.gov/pubmed/25788121
http://dx.doi.org/10.1038/srep09257

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