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Understanding the effect of alternative splicing in the folding and function of the second PDZ from Protein Tyrosine Phosphatase-BL
PDZ domains are the most prominent biological structural domains involved in protein-protein interactions in the human cell. The second PDZ domain of the protein tyrosine phosphatase BL (PDZ2) interacts and binds the C-termini of the tumour suppressor protein APC and of the LIM domain-containing pro...
Autores principales: | Di Silvio, Eva, Toto, Angelo, Bonetti, Daniela, Morrone, Angela, Gianni, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365404/ https://www.ncbi.nlm.nih.gov/pubmed/25788329 http://dx.doi.org/10.1038/srep09299 |
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