H3K36 Trimethylation-Mediated Epigenetic Regulation is Activated by Bam and Promotes Germ Cell Differentiation During Early Oogenesis in Drosophila

Epigenetic silencing is critical for maintaining germline stem cells in Drosophila ovaries. However, it remains unclear how the differentiation factor, Bag-of-marbles (Bam), counteracts transcriptional silencing. We found that the trimethylation of lysine 36 on histone H3 (H3K36me3), a modification...

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Detalles Bibliográficos
Autores principales: Mukai, Masanori, Hira, Seiji, Nakamura, Katsuhiro, Nakamura, Shoichi, Kimura, Hiroshi, Sato, Masanao, Kobayashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365480/
https://www.ncbi.nlm.nih.gov/pubmed/25572421
http://dx.doi.org/10.1242/bio.201410850

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