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Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway

BACKGROUND: Inflammation induced by oxidized low-density lipoprotein (ox-LDL) plays an important role in the pathogenesis of atherosclerosis. Recently, roles of autophagy against inflammation in the process of atherosclerosis have drawn increasing attention. Here, we tested the possible molecular me...

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Detalles Bibliográficos
Autores principales: Fan, Xiaodi, Wang, Jun, Hou, Jincai, Lin, Chengren, Bensoussan, Alan, Chang, Dennis, Liu, Jianxun, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365560/
https://www.ncbi.nlm.nih.gov/pubmed/25884210
http://dx.doi.org/10.1186/s12967-015-0450-z

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