The association between Salt-inducible kinase 2 (SIK2) and gamma isoform of the regulatory subunit B55 of PP2A (B55gamma) contributes to the survival of glioma cells under glucose depletion through inhibiting the phosphorylation of S6K

BACKGROUND: PPP2R2C encodes a gamma isoform of the regulatory subunit B55 subfamily consisting PP2A heterotrimeric with A and C subunits. Currently, the precise functions of B55gamma in cancer are still under investigating. In this project, we reported a novel function of B55gamma in the regulation...

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Detalles Bibliográficos
Autores principales: Li, Ya-nan, Cao, Yi-qun, Wu, Xi, Han, Guo-sheng, Wang, Lai-xing, Zhang, Yu-hui, Chen, Xin, Hao, Bin, Yue, Zhi-jian, Liu, Jian-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365562/
https://www.ncbi.nlm.nih.gov/pubmed/25792973
http://dx.doi.org/10.1186/s12935-015-0164-6

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