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Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel
Dental enamel has evolved to resist the most grueling conditions of mechanical stress, fatigue, and wear. Adding insult to injury, it is exposed to the frequently corrosive environment of the oral cavity. While its hierarchical structure is unrivaled in its mechanical resilience, heterogeneity in th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365691/ https://www.ncbi.nlm.nih.gov/pubmed/25852562 http://dx.doi.org/10.3389/fphys.2015.00057 |
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author | Gordon, Lyle M. Joester, Derk |
author_facet | Gordon, Lyle M. Joester, Derk |
author_sort | Gordon, Lyle M. |
collection | PubMed |
description | Dental enamel has evolved to resist the most grueling conditions of mechanical stress, fatigue, and wear. Adding insult to injury, it is exposed to the frequently corrosive environment of the oral cavity. While its hierarchical structure is unrivaled in its mechanical resilience, heterogeneity in the distribution of magnesium ions and the presence of Mg-substituted amorphous calcium phosphate (Mg-ACP) as an intergranular phase have recently been shown to increase the susceptibility of mouse enamel to acid attack. Herein we investigate the distribution of two important constituents of enamel, residual organic matter and inorganic carbonate. We find that organics, carbonate, and possibly water show distinct distribution patterns in the mouse enamel crystallites, at simple grain boundaries, and in the amorphous interphase at multiple grain boundaries. This has implications for the resistance to acid corrosion, mechanical properties, and the mechanism by which enamel crystals grow during amelogenesis. |
format | Online Article Text |
id | pubmed-4365691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-43656912015-04-07 Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel Gordon, Lyle M. Joester, Derk Front Physiol Physiology Dental enamel has evolved to resist the most grueling conditions of mechanical stress, fatigue, and wear. Adding insult to injury, it is exposed to the frequently corrosive environment of the oral cavity. While its hierarchical structure is unrivaled in its mechanical resilience, heterogeneity in the distribution of magnesium ions and the presence of Mg-substituted amorphous calcium phosphate (Mg-ACP) as an intergranular phase have recently been shown to increase the susceptibility of mouse enamel to acid attack. Herein we investigate the distribution of two important constituents of enamel, residual organic matter and inorganic carbonate. We find that organics, carbonate, and possibly water show distinct distribution patterns in the mouse enamel crystallites, at simple grain boundaries, and in the amorphous interphase at multiple grain boundaries. This has implications for the resistance to acid corrosion, mechanical properties, and the mechanism by which enamel crystals grow during amelogenesis. Frontiers Media S.A. 2015-03-19 /pmc/articles/PMC4365691/ /pubmed/25852562 http://dx.doi.org/10.3389/fphys.2015.00057 Text en Copyright © 2015 Gordon and Joester. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Gordon, Lyle M. Joester, Derk Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
title | Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
title_full | Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
title_fullStr | Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
title_full_unstemmed | Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
title_short | Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
title_sort | mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365691/ https://www.ncbi.nlm.nih.gov/pubmed/25852562 http://dx.doi.org/10.3389/fphys.2015.00057 |
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