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Dynamic reconfiguration of the language network preceding onset of speech in picture naming

Language production is a complex neural process that requires the interplay between multiple specialized cortical regions. We investigated modulations in large‐scale cortical networks underlying preparation for speech production by contrasting cortico‐cortical coherence for overt and silent picture...

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Autores principales: Liljeström, Mia, Kujala, Jan, Stevenson, Claire, Salmelin, Riitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365727/
https://www.ncbi.nlm.nih.gov/pubmed/25413681
http://dx.doi.org/10.1002/hbm.22697
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author Liljeström, Mia
Kujala, Jan
Stevenson, Claire
Salmelin, Riitta
author_facet Liljeström, Mia
Kujala, Jan
Stevenson, Claire
Salmelin, Riitta
author_sort Liljeström, Mia
collection PubMed
description Language production is a complex neural process that requires the interplay between multiple specialized cortical regions. We investigated modulations in large‐scale cortical networks underlying preparation for speech production by contrasting cortico‐cortical coherence for overt and silent picture naming in an all‐to‐all connectivity analysis. To capture transient, frequency‐specific changes in functional connectivity we analyzed the magnetoencephalography data in two consecutive 300‐ms time windows. Within the first 300 ms following picture onset beta frequency coherence was increased for overt naming in a network of regions comprising the bilateral parieto‐temporal junction and medial cortices, suggesting that overt articulation modifies selection processes involved in speech planning. In the late time window (300–600 ms after picture onset) beta‐range coherence was enhanced in a network that included the ventral sensorimotor and temporal cortices. Coherence in the gamma band was simultaneously reduced between the ventral motor cortex and supplementary motor area, bilaterally. The results suggest functionally distinct roles for beta (facilitatory) and gamma (suppressive) band interactions in speech production, with strong involvement of the motor cortex in both frequency bands. Overall, a striking difference in functional connectivity between the early and late time windows was observed, revealing the dynamic nature of large‐scale cortical networks that support language and speech. Our results demonstrate that as the naming task evolves in time, the global connectivity patterns change, and that these changes occur (at least) on the time‐scale of a few hundred milliseconds. More generally, these results bear implications for how we view large‐scale neural networks underlying task performance. Hum Brain Mapp 36:1202–1216, 2015. © 2014 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.
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spelling pubmed-43657272015-03-23 Dynamic reconfiguration of the language network preceding onset of speech in picture naming Liljeström, Mia Kujala, Jan Stevenson, Claire Salmelin, Riitta Hum Brain Mapp Research Articles Language production is a complex neural process that requires the interplay between multiple specialized cortical regions. We investigated modulations in large‐scale cortical networks underlying preparation for speech production by contrasting cortico‐cortical coherence for overt and silent picture naming in an all‐to‐all connectivity analysis. To capture transient, frequency‐specific changes in functional connectivity we analyzed the magnetoencephalography data in two consecutive 300‐ms time windows. Within the first 300 ms following picture onset beta frequency coherence was increased for overt naming in a network of regions comprising the bilateral parieto‐temporal junction and medial cortices, suggesting that overt articulation modifies selection processes involved in speech planning. In the late time window (300–600 ms after picture onset) beta‐range coherence was enhanced in a network that included the ventral sensorimotor and temporal cortices. Coherence in the gamma band was simultaneously reduced between the ventral motor cortex and supplementary motor area, bilaterally. The results suggest functionally distinct roles for beta (facilitatory) and gamma (suppressive) band interactions in speech production, with strong involvement of the motor cortex in both frequency bands. Overall, a striking difference in functional connectivity between the early and late time windows was observed, revealing the dynamic nature of large‐scale cortical networks that support language and speech. Our results demonstrate that as the naming task evolves in time, the global connectivity patterns change, and that these changes occur (at least) on the time‐scale of a few hundred milliseconds. More generally, these results bear implications for how we view large‐scale neural networks underlying task performance. Hum Brain Mapp 36:1202–1216, 2015. © 2014 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc. John Wiley and Sons Inc. 2014-11-21 /pmc/articles/PMC4365727/ /pubmed/25413681 http://dx.doi.org/10.1002/hbm.22697 Text en © 2014 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Liljeström, Mia
Kujala, Jan
Stevenson, Claire
Salmelin, Riitta
Dynamic reconfiguration of the language network preceding onset of speech in picture naming
title Dynamic reconfiguration of the language network preceding onset of speech in picture naming
title_full Dynamic reconfiguration of the language network preceding onset of speech in picture naming
title_fullStr Dynamic reconfiguration of the language network preceding onset of speech in picture naming
title_full_unstemmed Dynamic reconfiguration of the language network preceding onset of speech in picture naming
title_short Dynamic reconfiguration of the language network preceding onset of speech in picture naming
title_sort dynamic reconfiguration of the language network preceding onset of speech in picture naming
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365727/
https://www.ncbi.nlm.nih.gov/pubmed/25413681
http://dx.doi.org/10.1002/hbm.22697
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