Cargando…

Critical evaluation of Cbx7 downregulation in primary colon carcinomas and its clinical significance in Chinese patients

BACKGROUND: CBX7 is a Polycomb group protein that shows variable expression changes in various cancers that are often contradictive. A mouse knockout experiment has validated the tumor suppressor role in carcinogenesis. The purpose of this study is to verify the tumor suppressor role of Cbx7 in huma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Xiang, Zhou, Jing, Zhang, Baozhen, Zhang, Jun, Wilson, James, Gu, Liankun, Zhu, Budong, Gu, Jin, Ji, Jiafu, Deng, Dajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365772/ https://www.ncbi.nlm.nih.gov/pubmed/25881303 http://dx.doi.org/10.1186/s12885-015-1172-6

Ejemplares similares

Polycomb CBX7 Directly Controls Trimethylation of Histone H3 at Lysine 9 at the p16 Locus
por: Li, Qiang, et al.
Publicado: (2010)

P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7
por: Li, Zhuoqi, et al.
Publicado: (2022)

Corrigendum: P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7
por: Li, Zhuoqi, et al.
Publicado: (2022)

C-terminal in Sp1-like artificial zinc-finger proteins plays crucial roles in determining their DNA binding affinity
por: Zhang, Baozhen, et al.
Publicado: (2013)

miR663a-TTC22V1 axis inhibits colon cancer metastasis
por: Tian, Wei, et al.
Publicado: (2019)

P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis
por: Cui, Chenghua, et al.
Publicado: (2015)

CDKN2A Deletion Leading to Hematogenous Metastasis of Human Gastric Carcinoma
por: Qiao, Juanli, et al.
Publicado: (2021)

Significant impact of amount of PCR input templates on various PCR-based DNA methylation analysis and countermeasure
por: Liu, Zhaojun, et al.
Publicado: (2016)

CBX7 Modulates the Expression of Genes Critical for Cancer Progression
por: Pallante, Pierlorenzo, et al.
Publicado: (2014)

Identification of the Prognostic Biomarkers CBX6 and CBX7 in Bladder Cancer
por: Li, Xinxin, et al.
Publicado: (2023)

Kaiso phosphorylation at threonine 606 leads to its accumulation in the cytoplasm, reducing its transcriptional repression of the tumour suppressor CDH1
por: Tian, Wei, et al.
Publicado: (2022)

Single Nucleotide Polymorphisms of CBX4 and CBX7 Decrease the Risk of Hepatocellular Carcinoma
por: Tan, Chao, et al.
Publicado: (2019)

Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history
por: Liu, Zhuoqi, et al.
Publicado: (2008)

P16 Methylation Leads to Paclitaxel Resistance of Advanced Non-Small Cell Lung Cancer
por: Liu, Zhaojun, et al.
Publicado: (2019)

Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice
por: Tian, Yuan, et al.
Publicado: (2022)

Bone Marrow-Derived Cells May Not Be the Original Cells for Carcinogen-Induced Mouse Gastrointestinal Carcinomas
por: Yang, Chen, et al.
Publicado: (2013)

Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo
por: Du, Yantao, et al.
Publicado: (2012)

MALAT1–miR663a negative feedback loop in colon cancer cell functions through direct miRNA–lncRNA binding
por: Tian, Wei, et al.
Publicado: (2018)

Structure–Activity Relationships of Cbx7 Inhibitors, Including Selectivity Studies against Other Cbx Proteins
por: Simhadri, Chakravarthi, et al.
Publicado: (2016)

Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses
por: Zhou, He, et al.
Publicado: (2021)

P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib
por: Li, Paiyun, et al.
Publicado: (2019)

Oncogenic role of the chromobox protein CBX7 in gastric cancer
por: Zhang, Xiao-Wei, et al.
Publicado: (2010)

Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer
por: Iqbal, Mohammad Askandar, et al.
Publicado: (2021)

Pseudogenes and the associated ceRNA network as potential prognostic biomarkers for colorectal cancer
por: Li, Zhuoqi, et al.
Publicado: (2022)

LncRNA miR663AHG represses the development of colon cancer in a miR663a-dependent manner
por: Yuan, Hongfan, et al.
Publicado: (2023)

Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas
por: Xiang, Shengyan, et al.
Publicado: (2010)

Correction to: Expression and prognostic significance of CBX2 in colorectal cancer: database mining for CBX family members in malignancies and vitro analyses
por: Zhou, He, et al.
Publicado: (2021)

SRF promotes gastric cancer metastasis through stromal fibroblasts in an SDF1-CXCR4-dependent manner
por: Qiao, Juanli, et al.
Publicado: (2016)

Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation
por: Ding, Nan, et al.
Publicado: (2020)

Characterization of novel LncRNA P14AS as a protector of ANRIL through AUF1 binding in human cells
por: Ma, Wanru, et al.
Publicado: (2020)

CBX7, a Potential Prognostic Biomarker in Lung Adenocarcinoma
por: Yang, Yanlong, et al.
Publicado: (2021)

Cbx7 promotes the generation of induced pluripotent stem cells
por: Wang, Chie-Hong, et al.
Publicado: (2023)

CBX7 is Dualistic in Cancer Progression Based on its Function and Molecular Interactions
por: Li, Jun, et al.
Publicado: (2021)

miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene
por: Forzati, Floriana, et al.
Publicado: (2017)

Mining database for the clinical significance and prognostic value of CBX family in skin cutaneous melanoma
por: Li, Ding, et al.
Publicado: (2020)

CBX2 Inhibits Neurite Development by Regulating Neuron-Specific Genes Expression
por: Gu, Xi, et al.
Publicado: (2018)

Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration
por: Duan, Run-Shan, et al.
Publicado: (2018)

CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle
por: Fan, Yao, et al.
Publicado: (2017)

Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer
por: Tang, Jianjun, et al.
Publicado: (2014)

Prognostic significance of Cbx4 expression and its beneficial effect for transarterial chemoembolization in hepatocellular carcinoma
por: Jiao, H-K, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_e9iqtm4uruq4sa94asldglcmh5