Intrathecal administration of IGF-I by AAVrh10 improves sensory and motor deficits in a mouse model of diabetic neuropathy

Different adeno-associated virus (AAV) serotypes efficiently transduce neurons from central and peripheral nervous systems through various administration routes. Direct administration of the vectors to the cerebrospinal fluid (CSF) could be an efficient and safe strategy. Here, we show that lumbar p...

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Detalles Bibliográficos
Autores principales: Homs, Judit, Pagès, Gemma, Ariza, Lorena, Casas, Caty, Chillón, Miguel, Navarro, Xavier, Bosch, Assumpció
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365866/
https://www.ncbi.nlm.nih.gov/pubmed/26015946
http://dx.doi.org/10.1038/mtm.2013.7

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