Enhanced suicidal erythrocyte death in mice carrying a loss-of-function mutation of the adenomatous polyposis coli gene

Loss-of-function mutations in human adenomatous polyposis coli (APC) lead to multiple colonic adenomatous polyps eventually resulting in colonic carcinoma. Similarly, heterozygous mice carrying defective APC (apc(Min/+)) suffer from intestinal tumours. The animals further suffer from anaemia, which...

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Detalles Bibliográficos
Autores principales: Qadri, Syed M, Mahmud, Hasan, Lang, Elisabeth, Gu, Shuchen, Bobbala, Diwakar, Zelenak, Christine, Jilani, Kashif, Siegfried, Alexandra, Föller, Michael, Lang, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365887/
https://www.ncbi.nlm.nih.gov/pubmed/21781276
http://dx.doi.org/10.1111/j.1582-4934.2011.01387.x

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