IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice

Classical activation of macrophages (caMph or M1) is crucial for host protection against Mycobacterium tuberculosis (Mtb) infection. Evidence suggests that IL-4/IL-13 alternatively activated macrophages (aaMph or M2) are exploited by Mtb to divert microbicidal functions of caMph. To define the funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Guler, Reto, Parihar, Suraj P., Savvi, Suzana, Logan, Erin, Schwegmann, Anita, Roy, Sugata, Nieuwenhuizen, Natalie E., Ozturk, Mumin, Schmeier, Sebastian, Suzuki, Harukazu, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366092/
https://www.ncbi.nlm.nih.gov/pubmed/25790379
http://dx.doi.org/10.1371/journal.pone.0121070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366092/
https://www.ncbi.nlm.nih.gov/pubmed/25790379
http://dx.doi.org/10.1371/journal.pone.0121070

Ejemplares similares