Easy to Use Plastic Optical Fiber-Based Biosensor for Detection of Butanal

The final goal of this work is to achieve a selective detection of butanal by the realization of a simple, small-size and low cost experimental approach. To this end, a porcine odorant-binding protein was used in connection with surface plasmon resonance transduction in a plastic optical fiber tool...

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Detalles Bibliográficos
Autores principales: Cennamo, Nunzio, Di Giovanni, Stefano, Varriale, Antonio, Staiano, Maria, Di Pietrantonio, Fabio, Notargiacomo, Andrea, Zeni, Luigi, D’Auria, Sabato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366154/
https://www.ncbi.nlm.nih.gov/pubmed/25789470
http://dx.doi.org/10.1371/journal.pone.0116770
Descripción
Sumario:The final goal of this work is to achieve a selective detection of butanal by the realization of a simple, small-size and low cost experimental approach. To this end, a porcine odorant-binding protein was used in connection with surface plasmon resonance transduction in a plastic optical fiber tool for the selective detection of butanal by a competitive assay. This allows to reduce the cost and the size of the sensing device and it offers the possibility to design a “Lab-on-a-chip” platform. The obtained results showed that this system approach is able to selectively detect the presence of butanal in the concentration range from 20 μM to 1000 μM.

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