Cargando…
Cytoplasmic PELP1 and ERRgamma Protect Human Mammary Epithelial Cells from Tam-Induced Cell Death
Tamoxifen (Tam) is the only FDA-approved chemoprevention agent for pre-menopausal women at high risk for developing breast cancer. While Tam reduces a woman's risk of developing estrogen receptor positive (ER+) breast cancer, the molecular mechanisms associated with risk reduction are poorly un...
Autores principales: | Girard, Brian J., Regan Anderson, Tarah M., Welch, Siya Lem, Nicely, Julie, Seewaldt, Victoria L., Ostrander, Julie H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366195/ https://www.ncbi.nlm.nih.gov/pubmed/25789479 http://dx.doi.org/10.1371/journal.pone.0121206 |
Ejemplares similares
-
Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes
por: Daniel, Andrea R., et al.
Publicado: (2014) -
PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer
por: Truong, Thu H., et al.
Publicado: (2021) -
TAM-ing T cells in the tumor microenvironment: implications for TAM receptor targeting
por: Peeters, Marlies J. W., et al.
Publicado: (2019) -
Regulation of rDNA Transcription by Proto-Oncogene PELP1
por: Gonugunta, Vijay K., et al.
Publicado: (2011) -
Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR
por: Vadlamudi, Ratna K., et al.
Publicado: (2007)