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Liver Inflammation and Metabolic Signaling in Apc(Min/+) Mice: The Role of Cachexia Progression
The Apc(Min/+) mouse exhibits an intestinal tumor associated loss of muscle and fat that is accompanied by chronic inflammation, insulin resistance and hyperlipidemia. Since the liver governs systemic energy demands through regulation of glucose and lipid metabolism, it is likely that the liver is a...
Autores principales: | Narsale, Aditi A., Enos, Reilly T., Puppa, Melissa J., Chatterjee, Saurabh, Murphy, E. Angela, Fayad, Raja, Pena, Majorette O’, Durstine, J. Larry, Carson, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366213/ https://www.ncbi.nlm.nih.gov/pubmed/25789991 http://dx.doi.org/10.1371/journal.pone.0119888 |
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