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Mutational Analysis of Trypanosoma brucei RNA Editing Ligase Reveals Regions Critical for Interaction with KREPA2

The Trypanosoma brucei parasite causes the vector-borne disease African sleeping sickness. Mitochondrial mRNAs of T. brucei undergo posttranscriptional RNA editing to make mature, functional mRNAs. The final step of this process is catalyzed by the essential ligase, T. brucei RNA Editing Ligase 1 (T...

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Detalles Bibliográficos
Autores principales:	Mehta, Vaibhav, Sen, Rajashree, Moshiri, Houtan, Salavati, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366279/ https://www.ncbi.nlm.nih.gov/pubmed/25790471 http://dx.doi.org/10.1371/journal.pone.0120844

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