RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-κB-dependent inflammation

Mice with epidermal deletion of JunB transcription factor displayed a psoriasis-like inflammation. The relevance of these findings to humans and the mechanisms mediating JunB function are not fully understood. Here, we demonstrate that impaired JunB function via gene silencing or overexpression of a...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoling, Jin, Jane Y., Wu, Joseph, Qin, Xiaoxia, Streilein, Robert, Hall, Russell P., Zhang, Jennifer Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366298/
https://www.ncbi.nlm.nih.gov/pubmed/25501661
http://dx.doi.org/10.1038/jid.2014.519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366298/
https://www.ncbi.nlm.nih.gov/pubmed/25501661
http://dx.doi.org/10.1038/jid.2014.519

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