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PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines

While PCTAIRE1/PCTK1/Cdk16 is overexpressed in malignant cells and is crucial in tumorigenesis, its function in apoptosis remains unclear. Here we investigated the role of PCTAIRE1 in apoptosis, especially in the extrinsic cell death pathway. Gene-knockdown of PCTAIRE1 sensitized prostate cancer PPC...

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Detalles Bibliográficos
Autores principales:	Yanagi, Teruki, Shi, Ranxin, Aza-Blanc, Pedro, Reed, John C., Matsuzawa, Shu-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366397/ https://www.ncbi.nlm.nih.gov/pubmed/25790448 http://dx.doi.org/10.1371/journal.pone.0119404

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