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Gp78, an E3 Ubiquitin Ligase Acts as a Gatekeeper Suppressing Nonalcoholic Steatohepatitis (NASH) and Liver Cancer

Nonalcoholic steatohepatitis (NASH) is related to metabolic dysregulation and the perturbation of endoplasmic reticulum (ER) homeostasis that frequently develops into hepatocellular carcinoma (HCC). Gp78 is E3 ligase, which regulates endoplasmic reticulum-associated degradation (ERAD) by ubiquitinyl...

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Detalles Bibliográficos
Autores principales:	Zhang, Tianpeng, Kho, Dhong Hyo, Wang, Ying, Harazono, Yosuke, Nakajima, Kosei, Xie, Youming, Raz, Avraham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366401/ https://www.ncbi.nlm.nih.gov/pubmed/25789613 http://dx.doi.org/10.1371/journal.pone.0118448

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