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Antitumor Activity of a Polypyridyl Chelating Ligand: In Vitro and In Vivo Inhibition of Glioma

Glioblastoma multiforme is an extremely aggressive and invasive form of central nervous system tumor commonly treated with the chemotherapeutic drug Temozolomide. Unfortunately, even with treatment, the median survival time is less than 12 months. 2,9-Di-sec-butyl-1,10-phenanthroline (SBP), a phenan...

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Detalles Bibliográficos
Autores principales: David, Clément N., Frias, Elma S., Elix, Catherine C., McGovern, Kathryn E., Walker, Ameae M., Eichler, Jack F., Wilson, Emma H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366422/
https://www.ncbi.nlm.nih.gov/pubmed/25732707
http://dx.doi.org/10.1177/1759091415572365