Cargando…

Antitumor Activity of a Polypyridyl Chelating Ligand: In Vitro and In Vivo Inhibition of Glioma

Glioblastoma multiforme is an extremely aggressive and invasive form of central nervous system tumor commonly treated with the chemotherapeutic drug Temozolomide. Unfortunately, even with treatment, the median survival time is less than 12 months. 2,9-Di-sec-butyl-1,10-phenanthroline (SBP), a phenan...

Descripción completa

Detalles Bibliográficos
Autores principales:	David, Clément N., Frias, Elma S., Elix, Catherine C., McGovern, Kathryn E., Walker, Ameae M., Eichler, Jack F., Wilson, Emma H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366422/ https://www.ncbi.nlm.nih.gov/pubmed/25732707 http://dx.doi.org/10.1177/1759091415572365

Ejemplares similares

Synthesis, Characterization and Antitumor Activity of a Series of Polypyridyl Complexes
por: Liu, Jie, et al.
Publicado: (2000)

Photocytotoxicity and photoinduced phosphine ligand exchange in a Ru(ii) polypyridyl complex
por: Steinke, Sean J., et al.
Publicado: (2022)

Effects of Chemically-Modified Polypyridyl Ligands on the Structural and Redox Properties of Tricarbonylmanganese(I) Complexes
por: Kanno, Takatoshi, et al.
Publicado: (2020)

Structural and Photophysical Properties of Various Polypyridyl Ligands: A Combined Experimental and Computational Study
por: De Bruecker, Liesbeth, et al.
Publicado: (2020)

Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes
por: Herrera-Ramírez, Piedad, et al.
Publicado: (2023)

Ligand Rigidity Steers the Selectivity and Efficiency of the Photosubstitution Reaction of Strained Ruthenium Polypyridyl Complexes
por: Hakkennes, Matthijs L. A., et al.
Publicado: (2023)

Ruthenium polypyridyl complexes and their modes of interaction with DNA: Is there a correlation between these interactions and the antitumor activity of the compounds?
por: Corral, Eva, et al.
Publicado: (2008)

Promiscuous Ligands
por: McGovern, S.L.
Publicado: (2007)

Evaluation of the In Vitro and In Vivo Efficacy of Ruthenium Polypyridyl Compounds against Breast Cancer
por: Lenis-Rojas, Oscar A., et al.
Publicado: (2021)

Diastereoselective Synthesis and Two-Step Photocleavage of Ruthenium Polypyridyl Complexes Bearing a Bis(thioether) Ligand
por: Meijer, Michael S., et al.
Publicado: (2019)

Dark side illuminated: imaging of Toxoplasma gondii through the decades
por: McGovern, Kathryn E, et al.
Publicado: (2013)

Synthesis of O-1–O-6 Substituted Positional Isomers of d-Glucose–Thioether Ligands and Their Ruthenium Polypyridyl Conjugates
por: Lameijer, Lucien N., et al.
Publicado: (2018)

Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands
por: Griffith, Cynthia, et al.
Publicado: (2017)

Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(ii) polypyridyl complex
por: Gill, Martin R., et al.
Publicado: (2013)

Ruthenium(II) Polypyridyl Complexes Containing Simple Dioxo Ligands: a Structure‐Activity Relationship Study Shows the Importance of the Charge
por: Gandioso, Albert, et al.
Publicado: (2022)

The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells
por: Asperti, Michela, et al.
Publicado: (2019)

Data on the characterization and anticancer action of iron(II) polypyridyl complexes
por: Chen, Jingjing, et al.
Publicado: (2016)

Impact of Polypyridyl Ru Complexes on Angiogenesis—Contribution to Their Antimetastatic Activity
por: Gurgul, Ilona, et al.
Publicado: (2022)

Chemical control of competing electron transfer pathways in iron tetracyano-polypyridyl photosensitizers
por: Kunnus, Kristjan, et al.
Publicado: (2020)

A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis
por: Gill, Martin R., et al.
Publicado: (2022)

Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions
por: Denis, Mathieu, et al.
Publicado: (2018)

Evaluation of macrocyclic hydroxyisophthalamide ligands as chelators for zirconium-89
por: Bhatt, Nikunj B., et al.
Publicado: (2017)

Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes
por: Svensson, Frida R., et al.
Publicado: (2012)

Recent Developments in Hydrogen Evolving Molecular Cobalt(II)-Polypyridyl Catalysts
por: Queyriaux, N., et al.
Publicado: (2015)

Correction: Chiral ruthenium polypyridyl complexes as mitochondria-targeted apoptosis inducers
por: Chen, Tianfeng, et al.
Publicado: (2018)

Recent Advances on Octahedral Polypyridyl Ruthenium(II) Complexes as Antimicrobial Agents
por: Yang, Yulin, et al.
Publicado: (2018)

Octahedral ruthenium (II) polypyridyl complexes as antimicrobial agents against mycobacterium
por: Liao, Guojian, et al.
Publicado: (2017)

Photophysics and Cell Uptake of Self-Assembled Ru(II)Polypyridyl Vesicles
por: Finn, Stephen, et al.
Publicado: (2020)

Stabilization of Long-Looped i-Motif DNA by Polypyridyl Ruthenium Complexes
por: Pages, Benjamin J., et al.
Publicado: (2019)

Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery
por: Harun, Siti Norain, et al.
Publicado: (2021)

Electronic effects on polypyridyl Co complex-based water reduction catalysts
por: Guo, Xusheng, et al.
Publicado: (2021)

Selective, Disruptive Luminescent Ru(II) Polypyridyl Probes of G-Quadruplex
por: Holden, Lorcan, et al.
Publicado: (2023)

A Mechanism Study of Redox Reactions of the Ruthenium-oxo-polypyridyl Complex
por: Chen, Bao-Long, et al.
Publicado: (2023)

Adenine Radical Cation Formation by a Ligand-Centered Excited State of an Intercalated Chromium Polypyridyl Complex Leads to Enhanced DNA Photo-oxidation
por: Baptista, Frederico A., et al.
Publicado: (2021)

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii
por: David, Clément N., et al.
Publicado: (2016)

Towards the stable chelation of radium for biomedical applications with an 18-membered macrocyclic ligand
por: Abou, Diane S., et al.
Publicado: (2021)

Expansion of the Ligand Knowledge Base for Chelating P,P-Donor Ligands (LKB-PP)†
por: Jover, Jesús, et al.
Publicado: (2012)

Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation
por: Duan, Yu, et al.
Publicado: (2013)

The Antitumor Impact of Combining Hepatic Artery Ligation With Copper Chelators for Liver Cancer
por: Zeng, Ni, et al.
Publicado: (2023)

Ultrafast transient IR spectroscopy and DFT calculations of ruthenium(ii) polypyridyl complexes
por: Sun, Qinchao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5rksogktcv2rvgg9l660centgj