Chromatin organization at the nuclear pore favours HIV replication

The molecular mechanisms that allow HIV to integrate into particular sites of the host genome are poorly understood. Here we tested if the nuclear pore complex (NPC) facilitates the targeting of HIV integration by acting on chromatin topology. We show that the integrity of the nuclear side of the NP...

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Detalles Bibliográficos
Autores principales: Lelek, Mickaël, Casartelli, Nicoletta, Pellin, Danilo, Rizzi, Ermanno, Souque, Philippe, Severgnini, Marco, Di Serio, Clelia, Fricke, Thomas, Diaz-Griffero, Felipe, Zimmer, Christophe, Charneau, Pierre, Di Nunzio, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366494/
https://www.ncbi.nlm.nih.gov/pubmed/25744187
http://dx.doi.org/10.1038/ncomms7483

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