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Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease
Tissue fibrosis is a core pathologic process that contributes to mortality in ~45% of the population and is likely to be influenced by the host genetic architecture. Here we demonstrate, using liver disease as a model, that a single-nucleotide polymorphism (rs12979860) in the intronic region of inte...
Autores principales: | Eslam, Mohammed, Hashem, Ahmed M., Leung, Reynold, Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J., Chan, Henry L.K., Irving, William L., Sheridan, David, Abate, Maria L., Adams, Leon A., Mangia, Alessandra, Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Powell, Elizabeth, Nattermann, Jacob, Riordan, Stephen, McLeod, Duncan, Armstrong, Nicola J., Douglas, Mark W., Liddle, Christopher, Booth, David R., George, Jacob, Ahlenstiel, Golo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366528/ https://www.ncbi.nlm.nih.gov/pubmed/25740255 http://dx.doi.org/10.1038/ncomms7422 |
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