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Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

Tissue fibrosis is a core pathologic process that contributes to mortality in ~45% of the population and is likely to be influenced by the host genetic architecture. Here we demonstrate, using liver disease as a model, that a single-nucleotide polymorphism (rs12979860) in the intronic region of inte...

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Detalles Bibliográficos
Autores principales: Eslam, Mohammed, Hashem, Ahmed M., Leung, Reynold, Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J., Chan, Henry L.K., Irving, William L., Sheridan, David, Abate, Maria L., Adams, Leon A., Mangia, Alessandra, Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Powell, Elizabeth, Nattermann, Jacob, Riordan, Stephen, McLeod, Duncan, Armstrong, Nicola J., Douglas, Mark W., Liddle, Christopher, Booth, David R., George, Jacob, Ahlenstiel, Golo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366528/
https://www.ncbi.nlm.nih.gov/pubmed/25740255
http://dx.doi.org/10.1038/ncomms7422

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