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Paradoxical Response to Mechanical Unloading in Bone Loss, Microarchitecture, and Bone Turnover Markers
Background: Sclerostin, encoded by the SOST gene, has been implicated in the response to mechanical loading in bone. Some studies demonstrated that unloading leads to up-regulated SOST expression, which may induce bone loss. Purpose: Most reported studies regarding the changes caused by mechanical u...
Autores principales: | Sun, Xiaodi, Yang, Kaiyun, Wang, Chune, Cao, Sensen, Merritt, Mackenzie, Hu, Yingwei, Xu, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366632/ https://www.ncbi.nlm.nih.gov/pubmed/25798053 http://dx.doi.org/10.7150/ijms.11078 |
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