Cargando…

The assessment of an in-vitro model for evaluating the role of PARP in ethanol-mediated hepatotoxicity

This investigation aims to assess whether the hepatocellular carcinoma cell line, HepG2, is an appropriate model to assess the role of poly (ADP-ribose) polymerase (PARP) during acute ethanol toxicosis. HepG2 cells were dosed with graded concentrations of ethanol, ranging from 100 mM to 800 mM, for...

Descripción completa

Detalles Bibliográficos
Autores principales: Coyle, Jayme P, Mayo-Perez, A, Bourgeois, M, Johnson, G, Morris, S, Harbison, RD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366843/
https://www.ncbi.nlm.nih.gov/pubmed/25810958
http://dx.doi.org/10.4103/2229-5151.152300

Ejemplares similares