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The assessment of an in-vitro model for evaluating the role of PARP in ethanol-mediated hepatotoxicity
This investigation aims to assess whether the hepatocellular carcinoma cell line, HepG2, is an appropriate model to assess the role of poly (ADP-ribose) polymerase (PARP) during acute ethanol toxicosis. HepG2 cells were dosed with graded concentrations of ethanol, ranging from 100 mM to 800 mM, for...
Autores principales: | Coyle, Jayme P, Mayo-Perez, A, Bourgeois, M, Johnson, G, Morris, S, Harbison, RD |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366843/ https://www.ncbi.nlm.nih.gov/pubmed/25810958 http://dx.doi.org/10.4103/2229-5151.152300 |
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