Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature

Clozapine, an atypical antipsychotic, has been used in the treatment of schizophrenia and other psychotic disorders. Although it has good therapeutic effect but many a time it use is overridden by the associated adverse effects which range from minor to severe life-threatening events. There has been...

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Autores principales: Aneja, Jitender, Sharma, Nidhi, Mahajan, Sudhir, Chakrabarti, Subho, Grover, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366983/
https://www.ncbi.nlm.nih.gov/pubmed/25811003
http://dx.doi.org/10.4103/2249-4863.152269
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author Aneja, Jitender
Sharma, Nidhi
Mahajan, Sudhir
Chakrabarti, Subho
Grover, Sandeep
author_facet Aneja, Jitender
Sharma, Nidhi
Mahajan, Sudhir
Chakrabarti, Subho
Grover, Sandeep
author_sort Aneja, Jitender
collection PubMed
description Clozapine, an atypical antipsychotic, has been used in the treatment of schizophrenia and other psychotic disorders. Although it has good therapeutic effect but many a time it use is overridden by the associated adverse effects which range from minor to severe life-threatening events. There has been extensive literature for severe side effects like leukocytosis but limited data are available for transient eosinophilia. Here, we present two cases of benign transient eosinophilia and discuss the importance of recognizing eosinophilia while using clozapine.
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spelling pubmed-43669832015-03-25 Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature Aneja, Jitender Sharma, Nidhi Mahajan, Sudhir Chakrabarti, Subho Grover, Sandeep J Family Med Prim Care Case Report Clozapine, an atypical antipsychotic, has been used in the treatment of schizophrenia and other psychotic disorders. Although it has good therapeutic effect but many a time it use is overridden by the associated adverse effects which range from minor to severe life-threatening events. There has been extensive literature for severe side effects like leukocytosis but limited data are available for transient eosinophilia. Here, we present two cases of benign transient eosinophilia and discuss the importance of recognizing eosinophilia while using clozapine. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4366983/ /pubmed/25811003 http://dx.doi.org/10.4103/2249-4863.152269 Text en Copyright: © Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aneja, Jitender
Sharma, Nidhi
Mahajan, Sudhir
Chakrabarti, Subho
Grover, Sandeep
Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature
title Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature
title_full Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature
title_fullStr Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature
title_full_unstemmed Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature
title_short Eosinophilia Induced by Clozapine: A Report of Two Cases and Review of the Literature
title_sort eosinophilia induced by clozapine: a report of two cases and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366983/
https://www.ncbi.nlm.nih.gov/pubmed/25811003
http://dx.doi.org/10.4103/2249-4863.152269
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AT chakrabartisubho eosinophiliainducedbyclozapineareportoftwocasesandreviewoftheliterature
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