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Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing

Tumor suppressor genes BRCA1 and BRCA2 are the two main breast and ovarian cancer susceptibility genes, and their genetic testing has been used to evaluate the risk of hereditary breast and ovarian cancer (HBOC). While several studies have reported the prevalence of BRCA1 and BRCA2 mutations in Japa...

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Detalles Bibliográficos
Autores principales:	Hirotsu, Yosuke, Nakagomi, Hiroshi, Sakamoto, Ikuko, Amemiya, Kenji, Mochizuki, Hitoshi, Omata, Masao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367084/ https://www.ncbi.nlm.nih.gov/pubmed/25802882 http://dx.doi.org/10.1002/mgg3.120

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