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Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells

Vascular endothelial cells present luminal chemokines that arrest rolling leukocytes by activating integrins. It appears that several chemokines must form higher-order oligomers to elicit proper in vivo effects, as mutants restricted to forming dimers have lost the ability to recruit leukocytes to s...

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Detalles Bibliográficos
Autores principales:	Øynebråten, Inger, Barois, Nicolas, Bergeland, Trygve, Küchler, Axel M., Bakke, Oddmund, Haraldsen, Guttorm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367157/ https://www.ncbi.nlm.nih.gov/pubmed/25791723 http://dx.doi.org/10.1038/srep09261

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