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Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane

Targeting of the Gag polyprotein to the plasma membrane (PM) for assembly is a critical event in the late phase of immunodeficiency virus type-1 (HIV-1) infection. Gag binding to the PM is mediated by interactions between the myristoylated matrix (MA) domain and PM lipids. Despite the extensive bioc...

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Detalles Bibliográficos
Autores principales:	Vlach, Jiri, Saad, Jamil S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367181/ https://www.ncbi.nlm.nih.gov/pubmed/25852680 http://dx.doi.org/10.3389/fmicb.2015.00232

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