Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter

[Image: see text] The high-affinity choline transporter (CHT) is the rate-limiting determinant of acetylcholine (ACh) synthesis, yet the transporter remains a largely undeveloped target for the detection and manipulation of synaptic cholinergic signaling. To expand CHT pharmacology, we pursued a hig...

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Detalles Bibliográficos
Autores principales: Ennis, Elizabeth A., Wright, Jane, Retzlaff, Cassandra L., McManus, Owen B., Lin, Zhinong, Huang, Xiaofang, Wu, Meng, Li, Min, Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R., Blakely, Randy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367188/
https://www.ncbi.nlm.nih.gov/pubmed/25560927
http://dx.doi.org/10.1021/cn5001809

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