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Metabolic and cardiovascular complications in the liver transplant recipient

Metabolic syndrome (MS) is an established risk factor for atherosclerosis and cardiovascular disease that affects 20-30% of the adult population in the western world, correlating with increased incidence of cardiovascular disease. Survival following liver transplantation (LT) has been steadily impro...

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Detalles Bibliográficos
Autores principales: Luca, Laura De, Westbrook, Rachel, Tsochatzis, Emmanuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367207/
https://www.ncbi.nlm.nih.gov/pubmed/25830307
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author Luca, Laura De
Westbrook, Rachel
Tsochatzis, Emmanuel A.
author_facet Luca, Laura De
Westbrook, Rachel
Tsochatzis, Emmanuel A.
author_sort Luca, Laura De
collection PubMed
description Metabolic syndrome (MS) is an established risk factor for atherosclerosis and cardiovascular disease that affects 20-30% of the adult population in the western world, correlating with increased incidence of cardiovascular disease. Survival following liver transplantation (LT) has been steadily improving over the last 2 decades, with graft loss becoming a relatively rare cause of morbidity and mortality post LT. The improvement in short-term survival following LT has resulted in an increased incidence of metabolic and cardiovascular complications, which affect the mid- and long term survival. Patients following LT typically gain weight and might develop diabetes, hypertension and dyslipidemia as a consequence of their immunosuppressive therapy and their lifestyle. In this paper we review the prevalence of metabolic and cardiovascular complications following LT, their impact on post-transplant morbidity and mortality and their optimal management.
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spelling pubmed-43672072015-04-01 Metabolic and cardiovascular complications in the liver transplant recipient Luca, Laura De Westbrook, Rachel Tsochatzis, Emmanuel A. Ann Gastroenterol Invited Review Metabolic syndrome (MS) is an established risk factor for atherosclerosis and cardiovascular disease that affects 20-30% of the adult population in the western world, correlating with increased incidence of cardiovascular disease. Survival following liver transplantation (LT) has been steadily improving over the last 2 decades, with graft loss becoming a relatively rare cause of morbidity and mortality post LT. The improvement in short-term survival following LT has resulted in an increased incidence of metabolic and cardiovascular complications, which affect the mid- and long term survival. Patients following LT typically gain weight and might develop diabetes, hypertension and dyslipidemia as a consequence of their immunosuppressive therapy and their lifestyle. In this paper we review the prevalence of metabolic and cardiovascular complications following LT, their impact on post-transplant morbidity and mortality and their optimal management. Hellenic Society of Gastroenterology 2015 /pmc/articles/PMC4367207/ /pubmed/25830307 Text en Copyright: © Hellenic Society of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Review
Luca, Laura De
Westbrook, Rachel
Tsochatzis, Emmanuel A.
Metabolic and cardiovascular complications in the liver transplant recipient
title Metabolic and cardiovascular complications in the liver transplant recipient
title_full Metabolic and cardiovascular complications in the liver transplant recipient
title_fullStr Metabolic and cardiovascular complications in the liver transplant recipient
title_full_unstemmed Metabolic and cardiovascular complications in the liver transplant recipient
title_short Metabolic and cardiovascular complications in the liver transplant recipient
title_sort metabolic and cardiovascular complications in the liver transplant recipient
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367207/
https://www.ncbi.nlm.nih.gov/pubmed/25830307
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