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RNA Polymerase III Regulates Cytosolic RNA:DNA Hybrids and Intracellular MicroRNA Expression
RNA:DNA hybrids form in the nuclei and mitochondria of cells as transcription-induced R-loops or G-quadruplexes, but exist only in the cytosol of virus-infected cells. Little is known about the existence of RNA:DNA hybrids in the cytosol of virus-free cells, in particular cancer or transformed cells...
Autores principales: | Koo, Christine Xing'er, Kobiyama, Kouji, Shen, Yu J., LeBert, Nina, Ahmad, Shandar, Khatoo, Muznah, Aoshi, Taiki, Gasser, Stephan, Ishii, Ken J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367256/ https://www.ncbi.nlm.nih.gov/pubmed/25623070 http://dx.doi.org/10.1074/jbc.M115.636365 |
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