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Pyrrolidinyl caffeamide against ischemia/reperfusion injury in cardiomyocytes through AMPK/AKT pathways
BACKGROUND: Coronary heart disease is a leading cause of death in the world and therapy to reduce injury is still needed. The uncoupling of glycolysis and glucose oxidation induces lactate accumulation during myocardial ischemia/reperfusion (I/R) injury. Cell death occurs and finally leads to myocar...
Autores principales: | Lee, Shih-Yi, Ku, Hui-Chun, Kuo, Yueh-Hsiung, Chiu, His-Lin, Su, Ming-Jai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367820/ https://www.ncbi.nlm.nih.gov/pubmed/25879197 http://dx.doi.org/10.1186/s12929-015-0125-3 |
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