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Hunk/Mak-v is a negative regulator of intestinal cell proliferation

BACKGROUND: Conditional deletion of the tumour suppressor gene Apc within the murine intestine results in acute Wnt signalling activation. The associated over-expression of a myriad of Wnt signalling target genes yields phenotypic alterations that encompass many of the hallmarks of neoplasia. Previo...

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Detalles Bibliográficos
Autores principales: Reed, Karen R, Korobko, Igor V, Ninkina, Natalia, Korobko, Elena V, Hopkins, Ben R, Platt, James L, Buchman, Vladimir, Clarke, Alan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367870/
https://www.ncbi.nlm.nih.gov/pubmed/25881306
http://dx.doi.org/10.1186/s12885-015-1087-2