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VisualTE: a graphical interface for transposable element analysis at the genomic scale

BACKGROUND: Transposable elements are mobile DNA repeat sequences, known to have high impact on genes, genome structure and evolution. This has stimulated broad interest in the detailed biological studies of transposable elements. Hence, we have developed an easy-to-use tool for the comparative anal...

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Detalles Bibliográficos
Autores principales: Tempel, Sébastien, Talla, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367877/
https://www.ncbi.nlm.nih.gov/pubmed/25881276
http://dx.doi.org/10.1186/s12864-015-1351-5
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author Tempel, Sébastien
Talla, Emmanuel
author_facet Tempel, Sébastien
Talla, Emmanuel
author_sort Tempel, Sébastien
collection PubMed
description BACKGROUND: Transposable elements are mobile DNA repeat sequences, known to have high impact on genes, genome structure and evolution. This has stimulated broad interest in the detailed biological studies of transposable elements. Hence, we have developed an easy-to-use tool for the comparative analysis of the structural organization and functional relationships of transposable elements, to help understand their functional role in genomes. RESULTS: We named our new software VisualTE and describe it here. VisualTE is a JAVA stand-alone graphical interface that allows users to visualize and analyze all occurrences of transposable element families in annotated genomes. VisualTE reads and extracts transposable elements and genomic information from annotation and repeat data. Result analyses are displayed in several graphical panels that include location and distribution on the chromosome, the occurrence of transposable elements in the genome, their size distribution, and neighboring genes’ features and ontologies. With these hallmarks, VisualTE provides a convenient tool for studying transposable element copies and their functional relationships with genes, at the whole-genome scale, and in diverse organisms. CONCLUSIONS: VisualTE graphical interface makes possible comparative analyses of transposable elements in any annotated sequence as well as structural organization and functional relationships between transposable elements and other genetic object. This tool is freely available at: http://lcb.cnrs-mrs.fr/spip.php?article867. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-015-1351-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-43678772015-03-21 VisualTE: a graphical interface for transposable element analysis at the genomic scale Tempel, Sébastien Talla, Emmanuel BMC Genomics Software BACKGROUND: Transposable elements are mobile DNA repeat sequences, known to have high impact on genes, genome structure and evolution. This has stimulated broad interest in the detailed biological studies of transposable elements. Hence, we have developed an easy-to-use tool for the comparative analysis of the structural organization and functional relationships of transposable elements, to help understand their functional role in genomes. RESULTS: We named our new software VisualTE and describe it here. VisualTE is a JAVA stand-alone graphical interface that allows users to visualize and analyze all occurrences of transposable element families in annotated genomes. VisualTE reads and extracts transposable elements and genomic information from annotation and repeat data. Result analyses are displayed in several graphical panels that include location and distribution on the chromosome, the occurrence of transposable elements in the genome, their size distribution, and neighboring genes’ features and ontologies. With these hallmarks, VisualTE provides a convenient tool for studying transposable element copies and their functional relationships with genes, at the whole-genome scale, and in diverse organisms. CONCLUSIONS: VisualTE graphical interface makes possible comparative analyses of transposable elements in any annotated sequence as well as structural organization and functional relationships between transposable elements and other genetic object. This tool is freely available at: http://lcb.cnrs-mrs.fr/spip.php?article867. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-015-1351-5) contains supplementary material, which is available to authorized users. BioMed Central 2015-02-27 /pmc/articles/PMC4367877/ /pubmed/25881276 http://dx.doi.org/10.1186/s12864-015-1351-5 Text en © Tempel and Talla; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Tempel, Sébastien
Talla, Emmanuel
VisualTE: a graphical interface for transposable element analysis at the genomic scale
title VisualTE: a graphical interface for transposable element analysis at the genomic scale
title_full VisualTE: a graphical interface for transposable element analysis at the genomic scale
title_fullStr VisualTE: a graphical interface for transposable element analysis at the genomic scale
title_full_unstemmed VisualTE: a graphical interface for transposable element analysis at the genomic scale
title_short VisualTE: a graphical interface for transposable element analysis at the genomic scale
title_sort visualte: a graphical interface for transposable element analysis at the genomic scale
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367877/
https://www.ncbi.nlm.nih.gov/pubmed/25881276
http://dx.doi.org/10.1186/s12864-015-1351-5
work_keys_str_mv AT tempelsebastien visualteagraphicalinterfacefortransposableelementanalysisatthegenomicscale
AT tallaemmanuel visualteagraphicalinterfacefortransposableelementanalysisatthegenomicscale