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Novel genetic matching methods for handling population stratification in genome-wide association studies
BACKGROUND: A usually confronted problem in association studies is the occurrence of population stratification. In this work, we propose a novel framework to consider population matchings in the contexts of genome-wide and sequencing association studies. We employ pairwise and groupwise optimal case...
Autores principales: | Lacour, André, Schüller, Vitalia, Drichel, Dmitriy, Herold, Christine, Jessen, Frank, Leber, Markus, Maier, Wolfgang, Noethen, Markus M, Ramirez, Alfredo, Vaitsiakhovich, Tatsiana, Becker, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367953/ https://www.ncbi.nlm.nih.gov/pubmed/25880419 http://dx.doi.org/10.1186/s12859-015-0521-4 |
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