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Complex coding of endogenous siRNA, transcriptional silencing and H3K9 methylation on native targets of germline nuclear RNAi in C. elegans

BACKGROUND: Small RNA-guided transcriptional silencing (nuclear RNAi) is fundamental to genome integrity and epigenetic inheritance. Despite recent progress in identifying the capability and genetic requirements for nuclear RNAi in Caenorhabditis elegans, the natural targets and cellular functions o...

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Detalles Bibliográficos
Autores principales: Ni, Julie Zhouli, Chen, Esteban, Gu, Sam Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367959/
https://www.ncbi.nlm.nih.gov/pubmed/25534009
http://dx.doi.org/10.1186/1471-2164-15-1157