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Metronomic cyclophosphamide enhances HPV16E7 peptide vaccine induced antigen-specific and cytotoxic T-cell mediated antitumor immune response
In clinical trials, metronomic cyclophosphamide (CPA) is increasingly being combined with vaccines to reduce tumor-induced immune suppression. Previous strategies to modulate the immune system during vaccination have involved continuous administration of low dose chemotherapy, studies that have pose...
Autores principales: | Weir, Genevieve M, Hrytsenko, Olga, Stanford, Marianne M, Berinstein, Neil L, Karkada, Mohan, Liwski, Robert S, Mansour, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368141/ https://www.ncbi.nlm.nih.gov/pubmed/25960932 http://dx.doi.org/10.4161/21624011.2014.953407 |
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