Cargando…
Proinflammatory microenvironments within the intestine regulate differentiation of tissue-resident CD8 T cells responding to infection
We report that oral infection with Yersinia pseudotuberculosis (Yptb) results in development of two distinct populations of pathogen-specific CD8 tissue-resident memory T (T(RM)) cells in the lamina propria (LP). CD103(–) T cells did not require transforming-growth factor-β (TGF-β) signaling, but we...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368475/ https://www.ncbi.nlm.nih.gov/pubmed/25706747 http://dx.doi.org/10.1038/ni.3108 |