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Prediction of the Damage-Associated Non-Synonymous Single Nucleotide Polymorphisms in the Human MC1R Gene

The melanocortin 1 receptor (MC1R) is involved in the control of melanogenesis. Polymorphisms in this gene have been associated with variation in skin and hair color and with elevated risk for the development of melanoma. Here we used 11 computational tools based on different approaches to predict t...

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Detalles Bibliográficos
Autores principales: Hepp, Diego, Gonçalves, Gislene Lopes, de Freitas, Thales Renato Ochotorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368538/
https://www.ncbi.nlm.nih.gov/pubmed/25794181
http://dx.doi.org/10.1371/journal.pone.0121812