Cargando…

High Throughput Measurement of γH2AX DSB Repair Kinetics in a Healthy Human Population

The Columbia University RABiT (Rapid Automated Biodosimetry Tool) quantifies DNA damage using fingerstick volumes of blood. One RABiT protocol quantifies the total γ-H2AX fluorescence per nucleus, a measure of DNA double strand breaks (DSB) by an immunofluorescent assay at a single time point. Using...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Preety M., Ponnaiya, Brian, Taveras, Maria, Shuryak, Igor, Turner, Helen, Brenner, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368624/
https://www.ncbi.nlm.nih.gov/pubmed/25794041
http://dx.doi.org/10.1371/journal.pone.0121083