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Systematic Review on Irrational Use of Medicines in China and Vietnam
BACKGROUND: Irrational use of medicines has been an issue concerned all over the world and the outlooks in developing countries are more severe. This study aimed to assess the different patterns of irrational use of medicines and its influential factors in China and Vietnam. METHODS: A systematic re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368648/ https://www.ncbi.nlm.nih.gov/pubmed/25793497 http://dx.doi.org/10.1371/journal.pone.0117710 |
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author | Mao, Wenhui Vu, Huyen Xie, Zening Chen, Wen Tang, Shenglan |
author_facet | Mao, Wenhui Vu, Huyen Xie, Zening Chen, Wen Tang, Shenglan |
author_sort | Mao, Wenhui |
collection | PubMed |
description | BACKGROUND: Irrational use of medicines has been an issue concerned all over the world and the outlooks in developing countries are more severe. This study aimed to assess the different patterns of irrational use of medicines and its influential factors in China and Vietnam. METHODS: A systematic review was performed on both published and grey literatures in English, Chinese and Vietnamese languages between 1993 and 2013 based on the WHO framework. Quality assessment was conducted on the basis of the Critical Appraisal Skills Programme. Key indicators were analyzed to compare the irrational use of medicines in two countries. RESULTS: A total of 67 published works about China and 29 about Vietnam were included, the majority of which were cross-sectional prescription studies in both China and Vietnam. Irrational use of medicines was found in both the countries but issues with polypharmacy as well as overuse of antibiotics were more severe in Vietnam while overuse of injections was unique to China. Various patterns of irrational use were also indicated between urban and rural areas, and among different levels of hospitals. Rarely does literature focus on the analysis of influential factors of irrational use of medicines. While lack of proper knowledge from both providers and patients were the most recognized influential factors in both countries, economic incentives from pharmaceutical companies in China, and weak control and regulation over prescriptions in Vietnam were the main factors attributed to this issue. CONCLUSION: Severe irrational use of medicines has been abundantly evidenced in both China and Vietnam, highlighting the importance of policy interventions on the issue. However, limited evidence on the appropriateness or its compliance (conformity) to guidelines of prescription has been found. In addition, convincing evidence on the underlying explanation of this issue is lacking, although economic incentives, health insurance coverage, and knowledge of service providers and users have been implied to be factors influencing irrational drug use. |
format | Online Article Text |
id | pubmed-4368648 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-43686482015-03-27 Systematic Review on Irrational Use of Medicines in China and Vietnam Mao, Wenhui Vu, Huyen Xie, Zening Chen, Wen Tang, Shenglan PLoS One Research Article BACKGROUND: Irrational use of medicines has been an issue concerned all over the world and the outlooks in developing countries are more severe. This study aimed to assess the different patterns of irrational use of medicines and its influential factors in China and Vietnam. METHODS: A systematic review was performed on both published and grey literatures in English, Chinese and Vietnamese languages between 1993 and 2013 based on the WHO framework. Quality assessment was conducted on the basis of the Critical Appraisal Skills Programme. Key indicators were analyzed to compare the irrational use of medicines in two countries. RESULTS: A total of 67 published works about China and 29 about Vietnam were included, the majority of which were cross-sectional prescription studies in both China and Vietnam. Irrational use of medicines was found in both the countries but issues with polypharmacy as well as overuse of antibiotics were more severe in Vietnam while overuse of injections was unique to China. Various patterns of irrational use were also indicated between urban and rural areas, and among different levels of hospitals. Rarely does literature focus on the analysis of influential factors of irrational use of medicines. While lack of proper knowledge from both providers and patients were the most recognized influential factors in both countries, economic incentives from pharmaceutical companies in China, and weak control and regulation over prescriptions in Vietnam were the main factors attributed to this issue. CONCLUSION: Severe irrational use of medicines has been abundantly evidenced in both China and Vietnam, highlighting the importance of policy interventions on the issue. However, limited evidence on the appropriateness or its compliance (conformity) to guidelines of prescription has been found. In addition, convincing evidence on the underlying explanation of this issue is lacking, although economic incentives, health insurance coverage, and knowledge of service providers and users have been implied to be factors influencing irrational drug use. Public Library of Science 2015-03-20 /pmc/articles/PMC4368648/ /pubmed/25793497 http://dx.doi.org/10.1371/journal.pone.0117710 Text en © 2015 Mao et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Mao, Wenhui Vu, Huyen Xie, Zening Chen, Wen Tang, Shenglan Systematic Review on Irrational Use of Medicines in China and Vietnam |
title | Systematic Review on Irrational Use of Medicines in China and Vietnam |
title_full | Systematic Review on Irrational Use of Medicines in China and Vietnam |
title_fullStr | Systematic Review on Irrational Use of Medicines in China and Vietnam |
title_full_unstemmed | Systematic Review on Irrational Use of Medicines in China and Vietnam |
title_short | Systematic Review on Irrational Use of Medicines in China and Vietnam |
title_sort | systematic review on irrational use of medicines in china and vietnam |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368648/ https://www.ncbi.nlm.nih.gov/pubmed/25793497 http://dx.doi.org/10.1371/journal.pone.0117710 |
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