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Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations
Identifying driver mutations and their functional consequences is critical to our understanding of cancer. Towards this goal, and because domains are the functional units of a protein, we explored the protein domain-level landscape of cancer-type-specific somatic mutations. Specifically, we systemat...
Autores principales: | Yang, Fan, Petsalaki, Evangelia, Rolland, Thomas, Hill, David E., Vidal, Marc, Roth, Frederick P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368709/ https://www.ncbi.nlm.nih.gov/pubmed/25794154 http://dx.doi.org/10.1371/journal.pcbi.1004147 |
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