Packed Red Blood Cells Are an Abundant and Proximate Potential Source of Nitric Oxide Synthase Inhibition

OBJECTIVE: We determined, for packed red blood cells (PRBC) and fresh frozen plasma, the maximum content, and ability to release the endogenous nitric oxide synthase (NOS) inhibitors asymmetric dimethylarginine (ADMA) and monomethylarginine (LNMMA). BACKGROUND: ADMA and LNMMA are near equipotent NOS...

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Detalles Bibliográficos
Autores principales: Zwemer, Charles F., Davenport, Robertson D., Gomez-Espina, Juan, Blanco-Gonzalez, Elisa, Whitesall, Steven E., D'Alecy, Louis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368738/
https://www.ncbi.nlm.nih.gov/pubmed/25793525
http://dx.doi.org/10.1371/journal.pone.0119991

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