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Low Shear Stress Induced HMGB1 Translocation and Release via PECAM-1/PARP-1 Pathway to Induce Inflammation Response

Low shear stress (LSS) plays a critical role in the site predilection of atherosclerosis through activation of cellular mechanosensors, such as platelet endothelial cell adhesion molecule 1 (PECAM-1). Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme that regulates the expression of various...

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Detalles Bibliográficos
Autores principales:	Qin, Wei-dong, Mi, Shao-hua, Li, Chen, Wang, Gui-xia, Zhang, Jian-ning, Wang, Hao, Zhang, Fan, Ma, Yang, Wu, Da-wei, Zhang, Mingxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368774/ https://www.ncbi.nlm.nih.gov/pubmed/25793984 http://dx.doi.org/10.1371/journal.pone.0120586

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