Cargando…

Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children

BACKGROUND AND AIMS: The increase in overweight and obese children may be linked to increased rates of dyslipidaemia. The aim was to assess the prevalence of dyslipidaemia and associated risk factors among the Northern Mexican child population. METHODS AND RESULTS: Four hundred and fifty-one subject...

Descripción completa

Detalles Bibliográficos
Autores principales: Bibiloni, Maria del Mar, Salas, Rogelio, Novelo, Hilda I., Villarreal, Jesús Z., Sureda, Antoni, Tur, Josep A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368795/
https://www.ncbi.nlm.nih.gov/pubmed/25793380
http://dx.doi.org/10.1371/journal.pone.0119877
_version_ 1782362689180270592
author Bibiloni, Maria del Mar
Salas, Rogelio
Novelo, Hilda I.
Villarreal, Jesús Z.
Sureda, Antoni
Tur, Josep A.
author_facet Bibiloni, Maria del Mar
Salas, Rogelio
Novelo, Hilda I.
Villarreal, Jesús Z.
Sureda, Antoni
Tur, Josep A.
author_sort Bibiloni, Maria del Mar
collection PubMed
description BACKGROUND AND AIMS: The increase in overweight and obese children may be linked to increased rates of dyslipidaemia. The aim was to assess the prevalence of dyslipidaemia and associated risk factors among the Northern Mexican child population. METHODS AND RESULTS: Four hundred and fifty-one subjects aged between 2 and 10 (47.5% girls) took part in the Nuevo León State Survey of Nutrition and Health 2011–2012. According to the 2011 Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, serum lipid levels (mg/dL) were categorized into three subgroups (acceptable, borderline-high/low or high/low) as follows: TChol: acceptable <170, borderline-high 170–199, high ≥200; LDL-chol: acceptable <110, borderline-high 110–129, high ≥130; non-HDL-chol: acceptable <120, borderline-high 120–144, high ≥145; HDL-chol: acceptable >45, borderline-low 40–45, low <40; and TG: acceptable <75, borderline-high 75–99, high ≥100 in ≤9 year-old children, and acceptable <90, borderline-high 90–129, and high ≥130 in 10 year-old children. The overall prevalence of borderline-high + high TG, non-HDL-chol, TChol, and LDL-chol was 63.0%, 44.1%, 43.5%, and 29.9%, respectively. The overall prevalence of borderline-low + low HDL-chol was 46.3%. The overall frequency of dyslipidaemia was 54.3%. Thirteen children (2.9%) had all five symptoms of dyslipidaemia. The most common dyslipidaemia was high TG in combination (26.2%) and in isolation (10.6%). CONCLUSIONS: Half of the children had at least one abnormal lipid concentration. A high TG level was the most frequent dyslipidaemia. Obesity was associated with the occurrence of at least one abnormal lipid level. These findings emphasize the need to pay further attention to the prevention of cardiovascular disease and obesity from an early age.
format Online
Article
Text
id pubmed-4368795
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-43687952015-03-27 Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children Bibiloni, Maria del Mar Salas, Rogelio Novelo, Hilda I. Villarreal, Jesús Z. Sureda, Antoni Tur, Josep A. PLoS One Research Article BACKGROUND AND AIMS: The increase in overweight and obese children may be linked to increased rates of dyslipidaemia. The aim was to assess the prevalence of dyslipidaemia and associated risk factors among the Northern Mexican child population. METHODS AND RESULTS: Four hundred and fifty-one subjects aged between 2 and 10 (47.5% girls) took part in the Nuevo León State Survey of Nutrition and Health 2011–2012. According to the 2011 Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, serum lipid levels (mg/dL) were categorized into three subgroups (acceptable, borderline-high/low or high/low) as follows: TChol: acceptable <170, borderline-high 170–199, high ≥200; LDL-chol: acceptable <110, borderline-high 110–129, high ≥130; non-HDL-chol: acceptable <120, borderline-high 120–144, high ≥145; HDL-chol: acceptable >45, borderline-low 40–45, low <40; and TG: acceptable <75, borderline-high 75–99, high ≥100 in ≤9 year-old children, and acceptable <90, borderline-high 90–129, and high ≥130 in 10 year-old children. The overall prevalence of borderline-high + high TG, non-HDL-chol, TChol, and LDL-chol was 63.0%, 44.1%, 43.5%, and 29.9%, respectively. The overall prevalence of borderline-low + low HDL-chol was 46.3%. The overall frequency of dyslipidaemia was 54.3%. Thirteen children (2.9%) had all five symptoms of dyslipidaemia. The most common dyslipidaemia was high TG in combination (26.2%) and in isolation (10.6%). CONCLUSIONS: Half of the children had at least one abnormal lipid concentration. A high TG level was the most frequent dyslipidaemia. Obesity was associated with the occurrence of at least one abnormal lipid level. These findings emphasize the need to pay further attention to the prevention of cardiovascular disease and obesity from an early age. Public Library of Science 2015-03-20 /pmc/articles/PMC4368795/ /pubmed/25793380 http://dx.doi.org/10.1371/journal.pone.0119877 Text en © 2015 Bibiloni et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Bibiloni, Maria del Mar
Salas, Rogelio
Novelo, Hilda I.
Villarreal, Jesús Z.
Sureda, Antoni
Tur, Josep A.
Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children
title Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children
title_full Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children
title_fullStr Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children
title_full_unstemmed Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children
title_short Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children
title_sort serum lipid levels and dyslipidaemia prevalence among 2–10 year-old northern mexican children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368795/
https://www.ncbi.nlm.nih.gov/pubmed/25793380
http://dx.doi.org/10.1371/journal.pone.0119877
work_keys_str_mv AT bibilonimariadelmar serumlipidlevelsanddyslipidaemiaprevalenceamong210yearoldnorthernmexicanchildren
AT salasrogelio serumlipidlevelsanddyslipidaemiaprevalenceamong210yearoldnorthernmexicanchildren
AT novelohildai serumlipidlevelsanddyslipidaemiaprevalenceamong210yearoldnorthernmexicanchildren
AT villarrealjesusz serumlipidlevelsanddyslipidaemiaprevalenceamong210yearoldnorthernmexicanchildren
AT suredaantoni serumlipidlevelsanddyslipidaemiaprevalenceamong210yearoldnorthernmexicanchildren
AT turjosepa serumlipidlevelsanddyslipidaemiaprevalenceamong210yearoldnorthernmexicanchildren