Cargando…

Indications for Potential Parent-of-Origin Effects within the FTO Gene

Genome-Wide Association Studies (GWAS) were successfully applied to discover associations with obesity. However, the GWAS design is usually based on unrelated individuals and inheritance information on the parental origin of the alleles is missing. Taking into account parent-of-origin may provide fu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xuanshi, Hinney, Anke, Scholz, Markus, Scherag, André, Tönjes, Anke, Stumvoll, Michael, Stadler, Peter F., Hebebrand, Johannes, Böttcher, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368796/ https://www.ncbi.nlm.nih.gov/pubmed/25793382 http://dx.doi.org/10.1371/journal.pone.0119206

Ejemplares similares

Signatures of Natural Selection at the FTO (Fat Mass and Obesity Associated) Locus in Human Populations
por: Liu, Xuanshi, et al.
Publicado: (2015)

Eating disorders: the current status of molecular genetic research
por: Scherag, Susann, et al.
Publicado: (2009)

'Fat mass and obesity associated' gene (FTO): No significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents
por: Müller, Timo D, et al.
Publicado: (2008)

Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia
por: Knoll, Susanne, et al.
Publicado: (2008)

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)
por: Tan, Susanne, et al.
Publicado: (2010)

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis
por: Jarick, Ivonne, et al.
Publicado: (2011)

Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants
por: Hinney, Anke, et al.
Publicado: (2007)

Analysis of sequence variations in the suppressor of cytokine signaling (SOCS)-3 gene in extremely obese children and adolescents
por: Hölter, Katja, et al.
Publicado: (2007)

TAS2R38 and Its Influence on Smoking Behavior and Glucose Homeostasis in the German Sorbs
por: Keller, Maria, et al.
Publicado: (2013)

The role of rs2237781 within GRM8 in eating behavior
por: Gast, Marie-Therese, et al.
Publicado: (2013)

Investigation of a Genome Wide Association Signal for Obesity: Synthetic Association and Haplotype Analyses at the Melanocortin 4 Receptor Gene Locus
por: Scherag, André, et al.
Publicado: (2010)

From monogenic to polygenic obesity: recent advances
por: Hinney, Anke, et al.
Publicado: (2010)

Genetically programmed changes in transcription of the novel progranulin regulator
por: Keller, Maria, et al.
Publicado: (2020)

Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study
por: Wang, Hai-Jun, et al.
Publicado: (2016)

Successful Treatment with Atomoxetine of an Adolescent Boy with Attention Deficit/Hyperactivity Disorder, Extreme Obesity, and Reduced Melanocortin 4 Receptor Function
por: Pott, Wilfried, et al.
Publicado: (2013)

Gene Set of Nuclear-Encoded Mitochondrial Regulators Is Enriched for Common Inherited Variation in Obesity
por: Knoll, Nadja, et al.
Publicado: (2013)

Mutation screen and association studies in the Diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13
por: Friedel, Susann, et al.
Publicado: (2007)

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry
por: Vogel, Carla IG, et al.
Publicado: (2009)

Role of Vaspin in Human Eating Behaviour
por: Breitfeld, Jana, et al.
Publicado: (2013)

Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity
por: Müller, Timo D, et al.
Publicado: (2010)

Prevalence estimates of putatively pathogenic leptin variants in the gnomAD database
por: Rajcsanyi, Luisa Sophie, et al.
Publicado: (2022)

Genetic variants in AKR1B10 associate with human eating behavior
por: Rohde, Kerstin, et al.
Publicado: (2015)

Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
por: Müller, Timo Dirk, et al.
Publicado: (2008)

Increased constraints on MC4R during primate and human evolution
por: Hughes, David A., et al.
Publicado: (2008)

Evaluation of the MC3R gene pertaining to body weight and height regulation and puberty development
por: Zheng, Yiran, et al.
Publicado: (2023)

Identification of Adipokine Clusters Related to Parameters of Fat Mass, Insulin Sensitivity and Inflammation
por: Flehmig, Gesine, et al.
Publicado: (2014)

On the impact of relatedness on SNP association analysis
por: Gross, Arnd, et al.
Publicado: (2017)

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups
por: Vogel, Carla IG, et al.
Publicado: (2009)

Melanocortin-4 Receptor and Lipocalin 2 Gene Variants in Spanish Children with Abdominal Obesity: Effects on BMI-SDS after a Lifestyle Intervention
por: Morell-Azanza, Lydia, et al.
Publicado: (2019)

A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder
por: Libuda, Lars, et al.
Publicado: (2020)

Causal Effect of Age at Menarche on the Risk for Depression: Results From a Two-Sample Multivariable Mendelian Randomization Study
por: Hirtz, Raphael, et al.
Publicado: (2022)

(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distribution
por: Rohde, Kerstin, et al.
Publicado: (2019)

Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients – a randomized controlled trial: study protocol
por: Föcker, Manuel, et al.
Publicado: (2018)

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants
por: Volckmar, Anna-Lena, et al.
Publicado: (2012)

Adipokine Pattern in Subjects with Impaired Fasting Glucose and Impaired Glucose Tolerance in Comparison to Normal Glucose Tolerance and Diabetes
por: Tönjes, Anke, et al.
Publicado: (2010)

FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?
por: Landgraf, Kathrin, et al.
Publicado: (2016)

Interplay between adipose tissue secreted proteins, eating behavior and obesity
por: Würfel, Marleen, et al.
Publicado: (2021)

Meta-analysis on the effect of the N363S polymorphism of the glucocorticoid receptor gene (GRL) on human obesity
por: Marti, Amelia, et al.
Publicado: (2006)

The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study
por: Peters, Triinu, et al.
Publicado: (2020)

Suggestive Evidence for Causal Effect of Leptin Levels on Risk for Anorexia Nervosa: Results of a Mendelian Randomization Study
por: Peters, Triinu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vgenje46lt0g5h96b9ia9al5mq