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Characterization of a Novel Mutation in NS1 Protein of Influenza A Virus Induced by a Chemical Substance for the Attenuation of Pathogenicity
It is generally accepted that live attenuated influenza vaccine (LAIV) has the potential for use as a vaccination against flu. In this study, we demonstrated the nature of an influenza A virus (IAV) mutant induced by treating the IAV with a stable furan derivative, (1R,2R)-1-(5’-methylfur-3’-yl)prop...
Autores principales: | Sasaki, Kohei, Hayashi, Kyoko, Lee, Jung-Bum, Kurosaki, Fumiya, Hayashi, Toshimitsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368802/ https://www.ncbi.nlm.nih.gov/pubmed/25793397 http://dx.doi.org/10.1371/journal.pone.0121205 |
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